Topotecan Hydrochloride BP-EP-USP

Topotecan Hydrochloride BP-EP-USP Specification

Storage
Dry Place

Molecular Formula
C23H23N3O5.HCl

Molecular Weight
457.91

Boiling point
782.9 C at 760 mmH

Melting Point
213-218 C

Medicine Name
Topotecan Hydrochloride

Chemical Name
9-dihydroxy

CAS No
119413-54-6

Type
Pharmaceutical Intermediates

Grade
Industrial Grade

Usage
Pharmaceutical

Purity(%)
99%

Appearance
white crystalline solid

Physical Form
Powder

Topotecan Hydrochloride BP-EP-USP Trade Information

Minimum Order Quantity
1 Kilograms

Main Export Market(s)
Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

About Topotecan Hydrochloride BP-EP-USP

It is the hydrochloride salt of a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery.

Exceptional Pharmaceutical Quality

Topotecan Hydrochloride meets BP, EP, and USP standards, ensuring robust quality and consistency in pharmaceutical applications. Its industrial grade and high purity make it suitable for critical drug development processes, especially as an intermediate in anti-cancer formulations.

Optimized Formulation and Storage

Available as a white crystalline powder, Topotecan Hydrochloride should be stored in a dry, well-ventilated space to preserve its properties. The compounds reliable melting and boiling points support precise handling during pharmaceutical manufacturing.

FAQs of Topotecan Hydrochloride BP-EP-USP:

Q: How should Topotecan Hydrochloride be stored to maintain its stability?

A: Topotecan Hydrochloride should be kept in a dry place, away from moisture and direct sunlight, to preserve its chemical integrity and prevent degradation.

Q: What is the primary use of Topotecan Hydrochloride in the pharmaceutical industry?

A: This compound is primarily utilized as a pharmaceutical intermediate, especially in the development of chemotherapeutic medications that target cancer cells.

Q: When is Topotecan Hydrochloride typically employed during medicine formulation?

A: It serves as a key intermediate during the synthesis stage of pharmaceutical production, particularly for drugs requiring high purity and precise pharmacological action.

Q: Where is Topotecan Hydrochloride manufactured and exported from?

A: Our Topotecan Hydrochloride is manufactured, supplied, and exported from India, adhering to BP, EP, and USP standards for global pharmaceutical markets.

Q: What process ensures the high purity (99%) of Topotecan Hydrochloride?

A: The compound undergoes advanced purification and crystallization steps, with stringent quality controls at each phase to maintain a 99% purity standard.

Q: How is Topotecan Hydrochloride beneficial for drug manufacturers?

A: Its high chemical purity, stable physical form, and compliance with international standards make it a dependable choice for pharmaceutical companies developing anti-cancer medicines.

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