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Topotecan Hydrochloride BP-EP-USP

Topotecan Hydrochloride BP-EP-USP
Topotecan Hydrochloride BP-EP-USP

Topotecan Hydrochloride BP-EP-USP Specification

  • Molecular Weight
  • 457.91
  • Storage
  • Dry Place
  • Melting Point
  • 213-218 C
  • Boiling point
  • 782.9 C at 760 mmH
  • Molecular Formula
  • C23H23N3O5.HCl
  • Medicine Name
  • Topotecan Hydrochloride
  • Chemical Name
  • 9-dihydroxy
  • CAS No
  • 119413-54-6
  • Type
  • Pharmaceutical Intermediates
  • Grade
  • Industrial Grade
  • Usage
  • Pharmaceutical
  • Purity(%)
  • 99%
  • Appearance
  • white crystalline solid
  • Physical Form
  • Powder
 

Topotecan Hydrochloride BP-EP-USP Trade Information

  • Minimum Order Quantity
  • 1 Kilograms
  • Main Export Market(s)
  • Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa
 

About Topotecan Hydrochloride BP-EP-USP

It is the hydrochloride salt of a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. 
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