Terbutaline Sulphate BP - EP -USP

Terbutaline Sulphate BP - EP -USP Specification

Heavy Metal (%)
20ppm max

Molecular Weight
225.288

Shelf Life
5 Years

Melting Point
119 to 122

Molecular Formula
C12H19NO3

Storage
Dry Place

Loss on Drying
0.5%

Solubility
Soluble in water

CAS No
23031 25 6

Grade
Industrial Grade

Usage
Pharmaceutical

Purity(%)
98.0 - 101.0% ACIDITY

Appearance
white to off-white powder

Physical Form
Powder

Terbutaline Sulphate BP - EP -USP Trade Information

Minimum Order Quantity
10 Kilograms

Main Export Market(s)
Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

About Terbutaline Sulphate BP - EP -USP

Terbutaline Sulfateis the sulfate salt form of terbutaline, an ethanolamine derivative with bronchodilating and tocolyticproperties. Terbutaline sulfate selectively binds to and activates beta-2 adrenergicreceptors, leading to intracellular adenyl cyclase activation via a trimeric Gprotein and subsequent increase in cyclic cAMP production. Increased cAMP levels result in relaxation of bronchial and vascularsmooth muscle mediated through the activation of protein kinase A (PKA), whichphosphorylates proteins in control of muscle tone. cAMP also inhibits calcium ion release from intracellular stores, reduces calcium entry into cells and induces the sequestration ofintracellular calcium all of which aids the relaxation of airway muscles.Terbutaline sulfate also increases mucociliary clearance and reduces release ofinflammatory cell mediators

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