Clobetasol Propionate

Clobetasol Propionate Specification

Particle Size
Micronized

Loss on Drying
0.5%

Heavy Metal (%)
0.001%

Structural Formula
See Image

Taste
Bitter

Melting Point
195-200C

Molecular Weight
466.97 g/mol

Poisonous
Non-poisonous as supplied; For pharmaceutical use only

HS Code
29372900

Smell
Odorless

Storage
Dry Place

Solubility
Practically insoluble in water, soluble in methanol & ethanol

Molecular Formula
C25H32ClFO5

Shelf Life
5 Years

EINECS No
246-634-3

Medicine Name
Clobetasol Propionate

Chemical Name
Clobetasol Propionate

CAS No
25122-46-7

Type
Active Pharmaceutical Ingredient

Grade
Pharmaceutical Grade

Usage
Industrial

Purity(%)
99%

Appearance
Powder

Physical Form
Solid

Application
Used in topical formulations for treating skin disorders

Residue on Ignition
0.1%

Related Substances
Total impurities 1.0%

Specific Rotation
+103 to +110 (in methanol)

Assay (by HPLC)
99.0%

Packing
Export worthy HDPE drums with double polyethylene liners

Microbial Limits
As per Pharmacopoeia

Clobetasol Propionate Trade Information

Minimum Order Quantity
1 Unit

Main Export Market(s)
Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

About Clobetasol Propionate

Clobetasol propionate is an effective corticosteroid known for its ability to treat various skin conditions. It is formulated to alleviate symptoms of dermatitis, psoriasis, eczema, etc. In addition, it also ensures rapid relief from itching, redness, and swelling. It reduces the actions of chemicals in the body and inflammation, promoting skin healing. With speedy reactions and actions, this Clobetasol Propionate has become a preferred choice for treating acute flare-ups and chronic skin conditions. Its clinically proven formula also restores the natural balance of the skin.

Superior Quality and Purity

Clobetasol Propionate is manufactured to pharmaceutical-grade standards, ensuring a purity of at least 99%. Stringent testing is carried out for related substances, heavy metals, and microbial content, meeting global regulatory requirements. This guarantees both consistency and safety for pharmaceutical applications.

Precise Formulation and Packaging

Sourced from leading exporters and manufacturers in India, Clobetasol Propionate comes as a finely micronized powder for optimal incorporation in topical medicines. It is securely packed in HDPE drums with double polyethylene liners to maintain product stability and prevent contamination during export and storage.

Optimal Application and Storage

This API is primarily used in creams, ointments, and topical solutions for treating a range of skin disorders. The product should be stored in a dry place below 25C to preserve its stability and extend its shelf life, which is up to five years from manufacture when properly stored.

FAQs of Clobetasol Propionate:

Q: How is Clobetasol Propionate typically used in pharmaceutical applications?

A: Clobetasol Propionate is mainly used in the formulation of topical creams, ointments, and gels for the treatment of skin disorders such as eczema and psoriasis. It acts as a potent corticosteroid to reduce inflammation and itching.

Q: What quality standards does Clobetasol Propionate comply with?

A: The product adheres to stringent pharmaceutical grade criteria, featuring 99.0% purity by HPLC, residue on ignition 0.1%, total impurities 1.0%, heavy metals 0.001%, and complies with pharmacopoeial microbial limits.

Q: When should Clobetasol Propionate be stored for optimal shelf life?

A: For best results, store Clobetasol Propionate in a cool, dry place, away from direct sunlight and moisture. When stored correctly in its original packaging, the product maintains its quality for up to five years.

Q: Where is Clobetasol Propionate manufactured and exported from?

A: Clobetasol Propionate is produced and supplied by established manufacturers and exporters in India and is distributed globally in export-worthy packaging to ensure safe transit and delivery.

Q: What benefits does micronized Clobetasol Propionate offer in formulations?

A: The micronized form ensures uniform distribution in topical products, improving absorption and efficacy when applied to the skin. It also facilitates easy blending during the manufacturing process.

Q: What is the process for ensuring product safety and purity?

A: Comprehensive analytical methods such as HPLC analysis, impurity profiling, microbial testing, and residue analysis are used throughout production to guarantee that each batch meets international standards for purity and safety.

Q: What are the key factors to consider for Clobetasol Propionates use in industrial applications?

A: Besides its pharmaceutical use, industrial application requires verifying its purity, consistent particle size, and compatibility with other ingredients in a formulation to ensure product performance and compliance with regulatory standards.

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